We are pleased to inform you about our next study at the Surrey Clinical Research Centre (Surrey CRC) in Guildford. We are currently looking for healthy males and females to take part. The aim of the study is to assess the quality and duration of your sleep, and your level of alertness and ability to perform certain tasks in the evening before bed and in the morning after you wake up following an evening dose of either study drug, at two different doses (low and high dose), or placebo (dummy drug). Each group of participants will receive all 3 treatments in turn but in a different order.
Your sleep will be monitored and recorded during the night using electrodes attached to your body and scalp; this is called polysomnography (PSG). The PSG will record brain and muscle activities, eye movement, heart activity, airflow and any changes in your sleep or wakefulness.
You will be required to attend a medical screening session and if you pass that you will be invited in for a 1 night sleep assessment before being accepted onto the study. This will allow you to get used to the study sleep labs and we will also check for presence of any sleep disorders, which might exclude you from the study.
You will then be resident in the centre on 3 occasions, for a 1 night treatment period, with a washout period of 14 days between each visit. You will not know which medication you will be taking on each visit.
To be eligible to take part you must be:
A Healthy Male or Female aged 18-35 Years with a BMI of 18.5-30 kg/m2 and a weight of at least 50 kg
Taking no medication (except contraception)
A Non-smoker/not using nicotine replacement products for at least 6 months
Not have a history of any significant sleep problems
Available for the duration of the study (approximately 2 months)
On completion of the entire study, you will be reimbursed £800 for your time plus travel expenses. If you would like more information under no obligation, please contact the recruitment team on: 0800 269 847 or email firstname.lastname@example.org.